Takashi Wada Selected Research

Albumins

7/2022	Reduction in the magnitude of serum potassium elevation in combination therapy with esaxerenone (CS-3150) and sodium-glucose cotransporter 2 inhibitor in patients with diabetic kidney disease: Subanalysis of two phase III studies.
10/2021	Efficacy and safety of esaxerenone (CS-3150) in Japanese patients with type 2 diabetes and macroalbuminuria: a multicenter, single-arm, open-label phase III study.
8/2021	Decline in serum albumin concentration is a predictor of serious events in nonalcoholic fatty liver disease.
1/2021	Cysteinylated Albumin as a Potential Biomarker for the Progression of Kidney Disease in Patients With Type 2 Diabetes.
1/2021	Combined changes in albuminuria and kidney function and subsequent risk for kidney failure in type 2 diabetes.
12/2020	Esaxerenone (CS-3150) in Patients with Type 2 Diabetes and Microalbuminuria (ESAX-DN): Phase 3 Randomized Controlled Clinical Trial.
11/2020	Relationship between handgrip strength and albuminuria in community-dwelling elderly Japanese subjects: the Shika Study.
7/2020	Propagermanium administration for patients with type 2 diabetes and nephropathy: A randomized pilot trial.
1/2019	Nonproteinuric Versus Proteinuric Phenotypes in Diabetic Kidney Disease: A Propensity Score-Matched Analysis of a Nationwide, Biopsy-Based Cohort Study.
1/2019	Amplified Association Between Blood Pressure and Albuminuria in Overweight Patients With Biopsy-Proven Hypertensive Nephrosclerosis.

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Takashi Wada Research Topics

Disease

30	Proteinuria 02/2022 - 08/2000
28	Fibrosis (Cirrhosis) 12/2021 - 01/2003
27	Diabetic Nephropathies (Diabetic Nephropathy) 07/2022 - 03/2003
27	Chronic Renal Insufficiency 01/2022 - 02/2009
21	Glomerulonephritis 08/2022 - 08/2000
20	Neoplasms (Cancer) 12/2021 - 05/2002
18	Type 2 Diabetes Mellitus (MODY) 01/2022 - 10/2015
15	Chronic Kidney Failure (Chronic Renal Failure) 02/2022 - 04/2002
14	Inflammation (Inflammations) 12/2021 - 08/2000
12	Vasculitis (Vasculitides) 08/2022 - 08/2008
12	Albuminuria 07/2022 - 01/2012
10	Kidney Diseases (Kidney Disease) 03/2022 - 02/2009
10	Reperfusion Injury 01/2022 - 03/2002
10	Anemia 05/2021 - 01/2008
10	Necrosis 02/2021 - 03/2002
9	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 03/2020 - 10/2007
8	Acute Kidney Injury (Acute Renal Failure) 01/2022 - 02/2005
7	Nephrotic Syndrome (Syndrome, Nephrotic) 02/2022 - 05/2015
7	Lupus Nephritis 02/2021 - 12/2003
7	Infections 01/2021 - 03/2011
6	Renal Insufficiency (Renal Failure) 03/2022 - 01/2017
6	Neoplasm Metastasis (Metastasis) 11/2020 - 01/2002
6	Microscopic Polyangiitis 10/2016 - 10/2007
5	Diabetes Mellitus 03/2022 - 01/2007
5	Hypoxia (Hypoxemia) 01/2022 - 10/2002
5	Lipoid Nephrosis (Glomerulonephritis, Minimal Change) 01/2022 - 01/2002
5	Ureteral Obstruction 01/2021 - 07/2004
5	Pancreatic Neoplasms (Pancreatic Cancer) 11/2020 - 12/2017
5	IGA Glomerulonephritis (IGA Nephropathy) 01/2019 - 01/2006
5	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2016 - 01/2003
4	Cardiovascular Diseases (Cardiovascular Disease) 02/2022 - 01/2008
4	Ischemia 01/2022 - 10/2003
4	Disease Progression 01/2022 - 07/2014
4	Fatty Liver 12/2021 - 09/2013
4	Liver Cirrhosis (Hepatic Cirrhosis) 12/2021 - 06/2017
4	Pain (Aches) 07/2021 - 08/2017
4	Hematuria 01/2019 - 01/2006
3	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 01/2022 - 01/2002
3	Kidney Neoplasms (Kidney Cancer) 12/2021 - 09/2006
3	Hepatitis 08/2021 - 11/2013
3	Dyslipidemias (Dyslipidemia) 01/2021 - 06/2015
3	Peritoneal Fibrosis 01/2020 - 01/2012
3	Hyperuricemia 01/2020 - 01/2015
3	Liver Diseases (Liver Disease) 10/2019 - 01/2018
3	Hemorrhage 03/2018 - 10/2006

Drug/Important Bio-Agent (IBA)

20	CreatinineIBA 07/2022 - 04/2002
17	Proteins (Proteins, Gene)FDA Link 07/2022 - 04/2002
17	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 03/2020 - 12/2003
16	AlbuminsIBA 07/2022 - 02/2012
16	Biomarkers (Surrogate Marker)IBA 01/2022 - 02/2012
15	CytokinesIBA 01/2016 - 03/2002
13	ChemokinesIBA 01/2018 - 03/2002
10	AntibodiesIBA 02/2021 - 12/2003
9	Glucose (Dextrose)FDA LinkGeneric 07/2022 - 08/2011
9	Pharmaceutical PreparationsIBA 02/2022 - 05/2015
8	Messenger RNA (mRNA)IBA 01/2022 - 01/2002
8	Therapeutic UsesIBA 12/2021 - 04/2003
7	SodiumIBA 07/2022 - 01/2017
7	Hemoglobins (Hemoglobin)IBA 01/2022 - 06/2011
7	HematinicsIBA 05/2021 - 01/2018
7	AutoantibodiesIBA 02/2021 - 05/2004
7	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 10/2009 - 03/2002
6	LDL Lipoproteins (beta Lipoproteins)IBA 02/2022 - 04/2002
6	oxidized low density lipoproteinIBA 02/2022 - 05/2015
6	Serum AlbuminIBA 01/2022 - 01/2008
6	Erythropoietin Receptors (Erythropoietin Receptor)IBA 02/2021 - 11/2014
6	Erythropoietin FDA Link 01/2021 - 10/2002
6	EnzymesIBA 01/2020 - 01/2012
5	p38 Mitogen-Activated Protein KinasesIBA 01/2012 - 03/2002
4	Sodium-Glucose Transporter 2 InhibitorsIBA 07/2022 - 01/2019
4	SteroidsIBA 01/2022 - 05/2004
4	CanagliflozinIBA 01/2022 - 11/2020
4	Prednisolone (Predate)FDA LinkGeneric 01/2021 - 12/2009
4	CollagenIBA 02/2020 - 02/2011
4	Rituximab (Mabthera)FDA Link 06/2018 - 09/2010
4	Interleukin-6 (Interleukin 6)IBA 01/2017 - 01/2010
4	CCR2 ReceptorsIBA 01/2017 - 04/2004
4	Chemokine ReceptorsIBA 01/2012 - 12/2008
4	Immunoglobulin A (IgA)IBA 02/2007 - 01/2002
3	Peroxidase (Myeloperoxidase)IBA 08/2022 - 03/2012
3	Immunoglobulin G (IgG)IBA 07/2022 - 01/2008
3	esaxerenoneIBA 07/2022 - 12/2020
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 01/2012
3	Amino Acids FDA Link 01/2022 - 10/2018
3	4-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA 07/2021 - 12/2019
3	Darbepoetin alfa (Aranesp)FDA Link 02/2021 - 01/2018
3	IronIBA 02/2021 - 06/2011
3	Immunosuppressive Agents (Immunosuppressants)IBA 01/2021 - 12/2009
3	Transcription Factors (Transcription Factor)IBA 01/2021 - 10/2002
3	Gemcitabine FDA Link 11/2020 - 12/2017
3	propagermanium (Ge 132)IBA 07/2020 - 10/2003
3	Monoclonal AntibodiesIBA 01/2020 - 01/2007
3	Uric Acid (Urate)IBA 08/2018 - 01/2015

Therapy/Procedure

41	Therapeutics 07/2022 - 06/2002
11	Blood Component Removal (Apheresis) 02/2022 - 04/2002
6	Drug Therapy (Chemotherapy) 11/2020 - 12/2007
6	Renal Dialysis (Hemodialysis) 08/2018 - 01/2007
5	Hepatectomy 10/2019 - 01/2017
4	Nephrectomy 01/2022 - 01/2002
4	Transplantation 01/2016 - 09/2010